Tags

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ATG16L1
HLA-DRB1
IL10
IL12B
IL23R
IRGM
JAK2
LRRK2
MUC2
NOD2
SLC22A4
SLC22A5
STAT3
TYK2

Just in: SLC11A1, TPMT, ADAM17, FGFR1OP, HP and LACC1

It is becoming difficult to defend the notion that there is one Crohn Disease in the Irritable Bowel Syndromes (note the plural) category. Not that it matters much, but it seems likely that someone will venture a cladistics-like organization for this area – presumably based on what effects the various mutations have. Note that the MUC2 gene can have varying numbers of trinucleotide repeats – a very peculiar situation (and when it comes to human genetics that is saying a lot)

 

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